Internal Portfolio Development

Our mission is to work with scientists and clinicians at UPMC and any other academic or innovative institution to commercialize translational science, launch successful start-up companies, create partnerships and licensing opportunities with big pharma, and invest alongside top investors in external companies that complement our strategic focus.


The Beginning

Launched 17 projects in 2017 with $200M in funding icon image

Launched 17 projects in 2017 with $200M in funding

Initiated with a focus in Immune Therapy & Transplant icon image

Initiated with a focus in Immune Therapy & Transplant

A small team formed to commercialize leading-edge science icon image

A small team formed to commercialize leading-edge science

The Evolution

Additional funding ($1B total) in 2020 has enabled diverse set of investments

Spans early discovery to clinical initiation

Diligence in external investments complements internal pipeline and vice versa

Rigorous scientific, technical, and business diligence applied

Industry standard planning & execution ensure expeditious progress

What makes us successful?

Centers of Excellence and Expertise (University of Pittsburgh, Carnegie Mellon University) icon image

Centers of Excellence and Expertise (University of Pittsburgh, Carnegie Mellon University)

An end-to-end UPMC ecosystem (basic science to payor) icon image

An end-to-end UPMC ecosystem (basic science to payor)

Breadth and volume of innovation icon image

Breadth and volume of innovation

Ability to rapidly convert information to knowledge that shapes the opportunity icon image

Ability to rapidly convert information to knowledge that shapes the opportunity

Translational Sciences Team (diverse, seasoned, and nimble) icon image

Translational Sciences Team (diverse, seasoned, and nimble)

Ability to develop and execute industry standard translational plans icon image

Ability to develop and execute industry standard translational plans

Looking to the future

Expansion of team to grow internal pipeline

Greater outreach, beyond UPMC and University of Pittsburgh

Proactive idea intake and call for proposals

Commercial exits in addition to company formation

Building additional development capabilities

  • Manufacturing partners
  • Nonclinical development
  • Clinical and regulatory expertise

Are you interested in learning more about R&D collaboration with UPMC Enterprises? Please share your email address and we’ll be in touch with you shortly.