We are the innovators who are helping to find solutions to the complicated problems facing health care. United by our diverse backgrounds, we collaborate to draw upon each other’s unique skills and expertise.

We hire…

Engineering & Technology


Life Sciences

Business & Operations


Portfolio Companies

Engineering & Technology

  • Software Engineering & Architecture
  • Test Engineering
  • Technical Analysis
  • Scrum
  • Solutions Architecture
  • Technology Services Development & Delivery Management
  • Cybersecurity & Cloud Infrastructure
  • Machine Learning & Data Analytics
  • Data Engineering & Architecture

Our engineering team thrives on collaboration and curiosity to shift the paradigm and make an impact in the health care industry. Leveraging Agile methodology and the latest software platforms, you’ll work with product teams, clinicians, and data analysts to develop innovative health care technology. Plus, with access to leading clinical experts, you’ll gain real-world insights and feedback that enable you to iterate products to meet the needs of the end-user.


  • Strategic & Technical Product Management
  • Strategic & Product Design
  • Business Analytics
  • Portfolio Management & Development
  • Investment & Transaction Management
  • Program Management
  • Executives in Residence

Our product team has deep knowledge of health care IT and works to create and support innovations that will impact the lives of patients in meaningful, lasting ways. You’ll work alongside clinicians, researchers, and a collaborative team of expert engineers to transform ideas into thriving business and life changing medicine.

Life Sciences

  • Investment & Transaction Management
  • Business Analytics
  • Portfolio Management
  • Clinical & Scientific Research
  • Executives in Residence

UPMC Enterprises has a robust and rapidly growing Translational Sciences focus area dedicated to investing $1 billion in life sciences startups by 2024. The team collaborates with clinicians and industry experts to rapidly bring to market new drugs, diagnostics, and devices.

Business & Operations

  • Operations
  • Human Resources
  • Finance & Transaction Services
  • Legal
  • Marketing
  • Business Development

A wide range of specialties and skillsets are encompassed within the teams that make up the Business and Operations category. These experts provide critical vision and support to enhance the culture of Enterprises and boost the success of our portfolio. Whether leveraging systems and processes to help businesses run more efficiently, developing go-to-market strategies and tactics, or fostering industry relationships, you’ll be a key part of a collaborative team that is shaping the future of health care.


  • Product
  • Engineering & Technology Services
  • Life Sciences
  • Business & Operations

UPMC Enterprises Summer Associates work with mentors and gain valuable insight into all areas of our business. If you are interested in developing lasting relationships and gaining real-world exposure to the latest innovations in health care and technology, we encourage you to explore an opportunity with us.

Portfolio Companies

  • Product
  • Engineering & Technology Services
  • Life Sciences
  • Business & Operations

At UPMC Enterprises, we partner with select portfolio companies to grow their teams through our robust talent acquisition system. These startups are on the cutting-edge of science and technology and are looking for a variety of expertise to take their companies to the next level.

UPMC Enterprises is unlike anywhere you’ve ever worked. Our Bakery Square office is home to big thinkers and change makers. With us, you can feel free to dream big all while making life changing medicine happen.

Employee Spotlight

“The team is always willing to lean in and do whatever needs to be done to get the job done right.  There is a spirit of cooperation, curiosity, and drive for excellence that in many ways reminds me of my start-up days.”

Mary Beth Navarra-Sirio, MBA, RN

Vice President, Market Development

Digital Solutions

“I started my career in health care as a general surgeon. I am excited to now be taking a broader look at health care and help patients on a larger scale with investments in cutting-edge technologies.”

Harrison Lands, MD, MBA


Translational Sciences

“Everyone on the team is eager to share their insights, lend a helping hand and engage in constructive discussions. It’s this culture of collaboration that allows us to navigate complex decisions effectively and propose well-rounded investment strategies.”

Maryam Jalal, MS

Senior Associate, Transaction Services

Business Services

Guiding Principles

Our work is shaped by specific guiding principles designed to reflect our culture and our team.

Click on each principle to learn more.


Change makers. We drive the required changes in the future of health care across UPMC every day.


Relentless focus. We aggressively tackle problems as a team to create life-changing products.


Share, build, and achieve together. We achieve our mission as one, leveraging UPMC’s collective genius and holding one another accountable.


Relentless pursuit of knowledge. We seek knowledge and perspectives through persistent exploration, questioning, and learning, in order to deploy better solutions to health care problems.


Externally focused. We strive to positively impact the necessary cultural change in health care.


Own it and get it done. We commit to results and drive to success for ourselves, our team, our partners across UPMC, and our customers.

Join Us

Life at UPMC Enterprises

At UPMC Enterprises, we aim to break down the walls of the traditional workplace. Located in Pittsburgh’s thriving technology and life sciences scene, we embrace a casual dress code and enjoy a modern, open floor plan where our team can work both independently and collaboratively with developers, designers, and clinicians. From “Bring Your Dog to Work” days to virtual team-wide coffee chats, we pride ourselves on offering an agile atmosphere with the stability and backing of one of the nation’s largest integrated health systems.

“Shout-Ahts” of praise

Pittsburgh is a huge part of our culture at Enterprises. That is why we decided to get inspiration from Pittsburghese for “Shout-Ahts,” our peer-to-peer acknowledgement system for recognizing our colleagues who go above and beyond. Every month, we randomly select a Shout-Aht winner to win a cool prize as a thank you for all their hard work.

UPMCE team meeting in a conference room

All Hands on Deck

Once a month, UPMC Enterprises hosts an all staff presentation featuring updates from the president, project spotlights, HR updates, birthdays, anniversaries, and more. It’s a way for us to stay connected and to foster a sense of community. Oh, and sometimes, there’s cake.

UPMCE team walking outside

Location, location, location

Location, location, location! Our office is located in Bakery Square, the hub of innovation in Pittsburgh. In addition to having some very tech-savvy neighbors, we also get to take advantage of the hottest new restaurants, shops, and can’t-miss events in the city.

A dog in the office

Dog Days

At Enterprises, we welcome our furry friends to the office twice a month. We sometimes even invite them to write guest blogs in our “A Dog’s Day in the Life” series.