Greg Delgoffe, PhD

Senior Advisor

Greg M. Delgoffe is an Associate Professor of Immunology at the University of Pittsburgh, and Director of the Tumor Microenvironment Center at the UPMC Hillman Cancer Center. Dr. Delgoffe obtained his Ph.D at Johns Hopkins School of Medicine in 2010, and completed postdoctoral training at St. Jude Children’s Research Hospital.

Since its inception in 2014, Delgoffe’s lab has worked to both understand the metabolic deficiencies experienced by T cells as they infiltrate tumors and leverage that insight into metabolic strategies to bolster antitumor immunity. His group has shown metabolic defects are central to T cell dysfunction in cancer, suggesting all forms of immune-based therapy may be improved by metabolic modulation.

He has received multiple awards for innovation and contributions to science, including the Cancer Research Institute’s Lloyd J. Old STAR award, the Mark Foundation’s Emerging Leader award, the AACR NextGen Star Award, and the NIH Director’s New Innovator Award. Further, he has translated many of his observations at the bench into immunometabolic-based therapies for cancer.