Our story

In any profession, the best always have choices. Among entrepreneurs, the best are women and men with high integrity and brave ideas, along with grit, guts, and determination.

At UPMC Enterprises, we invest in the best. We help create health care innovations that will impact the lives of patients in meaningful, lasting ways.

To deliver on this promise, we’ve chosen a few focus areas where our insights about health care’s future give us a unique advantage.

We’ve built an impressive team with expertise in health care investing that’s second to none.

When we choose to work with an entrepreneur, we work side by side with them and provide full access to UPMC’s vast resources.

As an organization dedicated to Life Changing Medicine, UPMC has defined a bold mission: to shape the future of health care through innovation. At UPMC Enterprises, we help bring this mission to life by turning innovative ideas into growing, thriving businesses.

That’s why we want the best to choose UPMC Enterprises.

We wouldn’t have it any other way.

“The world is facing increasingly high rates of complex and nuanced chronic diseases. To achieve improved patient outcomes, digitization is critical to supporting better options in diagnosis and treatment. With UPMC and GE Healthcare, our mission at Omnyx is to transform pathology globally.”

Mamar Gelaye, Chief Executive Officer
Omnyx, a UPMC and GE Healthcare venture

Focus is what makes us unique

In the broad health care landscape, we’ve chosen to invest in a select number of areas where the challenges are great and the opportunities are massive.


Inventing the next generation of patient-centric technologies that will raise the standard of care and deliver higher-quality outcomes.


Helping payers and providers better manage risk and build new business models to capitalize on the shift from volume-based to value-based care.

health care

Developing automated, personalized applications that will empower consumers to become active participants in their own care.

Business services
and infrastructure

Creating solutions that use technology to streamline business processes and improve operational efficiency in healthcare.

Within these sectors, we participate in opportunities across all stages of development

  • With individuals and teams who have a business plan but no formal infrastructure in place
  • With early-stage companies who may have angel-round financing in place and are looking for a significant equity investor
  • With venture funds who are seeking additional participation in an existing company or partnership
  • With established companies seeking growth capital, joint ventures, or co-development partnerships

Exceptional companies don’t become exceptional by accident

By fully leveraging UPMC’s scale, reach, and collective insights about the future of health care, our portfolio companies and partners have been able to gain unique advantages over their competitors for nearly two decades. To learn more about our decades of experience and discuss how we might achieve success with you, we invite you to contact us.

Great people make all the difference

We’ve assembled a team of leaders with deep domain knowledge, a keen eye for talent, and a passion for building growing, thriving businesses.

Want to join us?

If you want to help us change the face of health care, UPMC Enterprises would like to hear from you. View current career opportunities or send your resume to a UPMC Enterprises recruiter.